A New Era in Ocular Therapeutics: Advanced Drug Delivery Systems for Uveitis and Neuro-Ophthalmologic Conditions

نویسندگان

چکیده

The eye’s intricate anatomical barriers pose significant challenges to the penetration, residence time, and bioavailability of topically applied medications, particularly in managing uveitis neuro-ophthalmologic conditions. Addressing this issue, polymeric nano-based drug delivery systems (DDS) have surfaced as a promising solution. These enhance hard-to-reach target tissues, extend time within ocular utilize biodegradable nanosized polymers reduce undesirable side effects. Thus, they stimulated substantial interest crafting innovative treatments for diseases. This review provides comprehensive exploration DDS used these We discuss present therapeutic hurdles posed by diseases explore potential role various biopolymers broadening our treatment repertoire. Our study incorporates detailed literature preclinical clinical studies from 2017 2023. Owing advancements polymer science, has made rapid strides, showing tremendous revolutionize patients with disorders.

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ژورنال

عنوان ژورنال: Pharmaceutics

سال: 2023

ISSN: ['1999-4923']

DOI: https://doi.org/10.3390/pharmaceutics15071952